Synthesis of novel 3-hydroxy-2-naphthoic hydrazones as selective chemosensors for cyanide ions.

ABSTRACT: The development of an effective and selective chemosensor for CN^- ions has become the need of the hour due to their hazardous impact on the environment and humans. Herein, we report the synthesis of two novel chemosensors, IF-1 and IF-2 based on 3-hydroxy-2-naphthohydrazide and aldehyde derivatives that have shown selective sensing of CN^- ions. IF-2 exhibited exclusive binding with CN^- ions that is further confirmed by the binding constant value of 4.77 × 10⁴ M^-1 with a low detection limit (8.2 μM). The chemosensory potential is attributed to deprotonation of the labile Schiff base center by CN^- ions that results in a color change from colorless to yellow as visible by the naked eye. Accompanying this, a DFT study was also p

SUBMITTER: Alharthy RD 

PROVIDER: S-EPMC10193203 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature