Motor speech effects in subthalamic deep brain stimulation for Parkinson's disease.

ABSTRACT:

Objective

A motor speech disorder or dysarthria commonly arises in patients with Parkinson's disease (PD). The impact of subthalamic nucleus (STN) deep brain stimulation (DBS) on motor speech and the potential of intraoperative motor speech testing to predict outcomes are unknown. This study examined 1) the types and prevalence of motor speech changes observed with STN DBS and their relation to the preoperative condition, 2) the ability of intraoperative testing to predict postoperative changes in motor speech, and 3) the spatial relationship between stimulation sites producing maximal motor improvement, as measured by the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS), and maximal motor speech deterioration.

Methods

Comprehensive preoperative

SUBMITTER: Kluin KJ 

PROVIDER: S-EPMC10193494 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature