Dataset Information

Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes.

ABSTRACT:

Background

Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated.

Methods

We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females.

Results

Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM.

Conclusions

Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. Grip strength and thigh SF thickness might serve as predictors for detection of osteoporosis in patients with T2DM.

SUBMITTER: Lu CH

PROVIDER: S-EPMC10193705 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature

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Publications

Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes.

Lu Chieh-Hua CH Lee Chien-Hsing CH Wu Li-Wei LW Liao Chun-Cheng CC Su Sheng-Chiang SC Liu Jhih-Syuan JS Li Peng-Fei PF Huang Chia-Luen CL Ho Li-Ju LJ Lin Chien-Ming CM Lin Ming-Hsun MH Chang Chun-Yung CY Liu Yi-Chen YC Lin Chih-Ping CP Cheng An-Che AC Kuo Feng-Chih FC

Diabetology & metabolic syndrome 20230518 1

<h4>Background</h4>Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated.<h4>Methods</h4>We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and ...[more]

PMID: 37198661

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Dataset Information

Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes.

Background

Methods

Results

Conclusions

Publications

Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes.

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