Arabidopsis thaliana: a powerful model organism to explore histone modifications and their upstream regulations.

ABSTRACT: Histones are subjected to extensive covalent modifications that affect inter-nucleosomal interactions as well as alter chromatin structure and DNA accessibility. Through switching the corresponding histone modifications, the level of transcription and diverse downstream biological processes can be regulated. Although animal systems are widely used in studying histone modifications, the signalling processes that occur outside the nucleus prior to histone modifications have not been well understood due to the limitations including non viable mutants, partial lethality, and infertility of survivors. Here, we review the benefits of using Arabidopsis thaliana as the model organism to study histone modifications and their upstream regulations. Similarities among histones and key histone m

SUBMITTER: Yu Y 

PROVIDER: S-EPMC10193919 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature