A Monte Carlo simulation for Moving Light Source in Intracavity PDT.

ABSTRACT: We developed a simulation method for modeling the light fluence delivery in intracavity Photodynamic Therapy (icav-PDT) for pleural lung cancer using a moving light source. Due to the large surface area of the pleural lung cavity, the light source needs to be moved to deliver a uniform dose around the entire cavity. While multiple fixed detectors are used for dosimetry at a few locations, an accurate simulation of light fluence and fluence rate is still needed for the rest of the cavity. We extended an existing Monte Carlo (MC) based light propagation solver to support moving light sources by densely sampling the continuous light source trajectory and assigning the proper number of photon packages launched along the way. The performance of Simphotek GPU CUDA-based implementation of

SUBMITTER: Parilov E 

PROVIDER: S-EPMC10194003 | biostudies-literature | 2023 Jan-Feb

REPOSITORIES: biostudies-literature