Muscle preflex response to perturbations in locomotion: In vitro experiments and simulations with realistic boundary conditions.

ABSTRACT: Neuromuscular control loops feature substantial communication delays, but mammals run robustly even in the most adverse conditions. In vivo experiments and computer simulation results suggest that muscles' preflex-an immediate mechanical response to a perturbation-could be the critical contributor. Muscle preflexes act within a few milliseconds, an order of magnitude faster than neural reflexes. Their short-lasting action makes mechanical preflexes hard to quantify in vivo. Muscle models, on the other hand, require further improvement of their prediction accuracy during the non-standard conditions of perturbed locomotion. Our study aims to quantify the mechanical work done by muscles during the preflex phase (preflex work) and test their mechanical force modulation. We perfor

SUBMITTER: Araz M 

PROVIDER: S-EPMC10194126 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature