Use of admission serum neutrophil gelatinase-associated lipocalin (NGAL) concentrations as a marker of sepsis and outcome in neonatal foals.

ABSTRACT:

Background

Equine neonatal sepsis can be challenging to diagnose and prognosticate. Neutrophil gelatinase-associated lipocalin (NGAL), a new marker of renal damage and inflammation, can potentially be helpful.

Objectives

To evaluate NGAL in neonatal foals with sepsis, and assess its relation to outcome.

Animals

Foals ≤ 14 days, with admission blood analysis and stored serum.

Methods

NGAL was measured on stored serum from 91 foals. Foals were scored for sepsis and survival and categorized according to sepsis status (septic, sick non-septic, healthy, and uncertain sepsis status) and outcome groups (survivors and non-survivors). The septic foals were further sub-categorized according to severity (normal sepsis, severe sepsis and septic shock). A Kruskal-Wallis tes

SUBMITTER: Laurberg M 

PROVIDER: S-EPMC10194986 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature