An expanded role for surgery in grade 3 1p/19q co-deleted oligodendroglioma.

ABSTRACT:

Background

Grade 3 1p/19q co-deleted oligodendroglioma is an uncommon primary CNS tumor with a high rate of progression and recurrence. This study examines the benefit of surgery after progression and identifies predictors of survival.

Methods

This is a single-institution retrospective cohort study of consecutive adult patients with anaplastic or grade 3 1p/19q co-deleted oligodendroglioma diagnosed between 2001 and 2020.

Results

Eighty patients with 1p/19q co-deleted grade 3 oligodendroglioma were included. The median age was 47 years (interquartile range 38-56) and 38.8% were women. All patients underwent surgery, including gross total resection (GTR) for 26.3% of patients, subtotal resection (STR) for 70.0% of patients, and biopsy for 3.8% of patients. Forty-three

SUBMITTER: Gupta S 

PROVIDER: S-EPMC10195195 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature