Duration-response association between occupational exposure and pancreatic cancer risk: meta-analysis.

ABSTRACT:

Background

Evidence is lacking on the occupational exposure time window to chemical agents related to pancreatic cancer risk.

Aims

This study performed meta-regression and meta-analysis to examine the dose-response association between occupational exposure duration to chemical agents and pancreatic cancer risk.

Methods

We searched and reviewed studies on exposure duration and pancreatic cancer in five databases (Cochrane Library, EMBASE, PubMed, ScienceDirect and Web of Science) from inception to 16 May 2022. Exposure refers to the years a worker was exposed to any chemical agent, and outcome variables were pancreatic cancer incidence and mortality.

Results

We identified 31 studies, including 288 389 participants. In the meta-regression, the positive dose-respo

SUBMITTER: Boonhat H 

PROVIDER: S-EPMC10195200 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature