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Genetic analysis of sliding motility in Mycobacterium smegmatis.


ABSTRACT: A screen for nonsliding mutants of Mycobacterium smegmatis yielded 20 mutants with transposon insertions in the mps gene, which is involved in glycopeptidolipid biosynthesis. One mutant had an insertion in a gene predicted to encode a membrane transport protein. All mutants lacked glycopeptidolipids and were unable to form biofilms on polyvinyl chloride.

SUBMITTER: Recht J 

PROVIDER: S-EPMC101957 | biostudies-literature | 2000 Aug

REPOSITORIES: biostudies-literature

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Genetic analysis of sliding motility in Mycobacterium smegmatis.

Recht J J   Martínez A A   Torello S S   Kolter R R  

Journal of bacteriology 20000801 15


A screen for nonsliding mutants of Mycobacterium smegmatis yielded 20 mutants with transposon insertions in the mps gene, which is involved in glycopeptidolipid biosynthesis. One mutant had an insertion in a gene predicted to encode a membrane transport protein. All mutants lacked glycopeptidolipids and were unable to form biofilms on polyvinyl chloride. ...[more]

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