Exercise and Prediabetes After Renal Transplantation (EXPRED-I): A Prospective Study.

ABSTRACT:

Background

Post-transplant diabetes mellitus (PTDM) beyond 12 months (late PTDM) is a severe complication after renal transplantation. Late PTDM develops mostly in subjects with prediabetes. Although exercise may have a potential role in preventing late PTDM, there are no previous data on the effect of exercise in patients with prediabetes.

Material and methods

The design was a 12-month exploratory study to test the capacity of exercise in reverting prediabetes in order to prevent late-PTDM. The outcome was the reversibility of prediabetes, assessed every 3 months with oral glucose tolerance tests (OGTT). The protocol included an incremental plan of aerobic and/or strength training as well as an active plan for promoting adherence (telephone calls, digital technology, and vi

SUBMITTER: Morales Febles R 

PROVIDER: S-EPMC10195924 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature