The spatial ventricular gradient is associated with adverse outcomes in acute pulmonary embolism.

ABSTRACT:

Background

The spatial ventricular gradient (SVG) is a vectorcardiographic measurement that reflects cardiac loading conditions via electromechanical coupling.

Objectives

We hypothesized that the SVG is correlated with right ventricular (RV) strain and is prognostic of adverse events in patients with acute pulmonary embolism (PE).

Methods

Retrospective, single-center study of patients with acute PE. Electrocardiogram (ECG), imaging, and outcome data were obtained. SVG components were regressed on tricuspid annular plane systolic excursion (TAPSE), qualitative RV dysfunction, and RV/left ventricular (LV) ratio. Odds of adverse outcomes (30-day mortality, vasopressor requirement, or advanced therapy) after PE were regressed on demographics, RV/LV ratios, traditional ECG

SUBMITTER: Stabenau HF 

PROVIDER: S-EPMC10196094 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature