Vibrio cholerae, classification, pathogenesis, immune response, and trends in vaccine development.

ABSTRACT: Vibrio cholerae is the causative agent of cholera, a highly contagious diarrheal disease affecting millions worldwide each year. Cholera is a major public health problem, primarily in countries with poor sanitary conditions and regions affected by natural disasters, where access to safe drinking water is limited. In this narrative review, we aim to summarize the current understanding of the evolution of virulence and pathogenesis of V. cholerae as well as provide an overview of the immune response against this pathogen. We highlight that V. cholerae has a remarkable ability to adapt and evolve, which is a global concern because it increases the risk of cholera outbreaks and the spread of the disease to new regions, making its control even more challenging. Furthermore,

SUBMITTER: Montero DA 

PROVIDER: S-EPMC10196187 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature