Clinical Outcomes of Intensity Modulated Proton Therapy Reirradiation for Gynecologic Malignancies.

ABSTRACT:

Purpose

Pelvic reirradiation (re-RT) for patients with gynecologic cancers remains a challenge because of toxicity concerns. Given the dosimetric advantages of proton therapy, we aimed to assess oncologic and toxicity outcomes of patients with re-RT to the pelvis/abdomen with intensity modulated proton therapy (IMPT) for gynecologic cancers.

Methods and materials

We performed a retrospective analysis of all patients with gynecologic cancer treated at a single institution between 2015 and 2021 with IMPT re-RT. Patients were included for analysis if the IMPT plan had at least partial overlap with the treated volume of a previous radiation treatment.

Results

A total of 29 patients were included for analysis, with 30 total courses of re-RT. The majority of patients had be

SUBMITTER: Pollock AE 

PROVIDER: S-EPMC10196228 | biostudies-literature | 2023 Jul-Aug

REPOSITORIES: biostudies-literature