C-reactive protein and procalcitonin during course of sepsis and septic shock.

ABSTRACT:

Objective

The study investigates the diagnostic and prognostic value of C-reactive protein (CRP) and procalcitonin (PCT) in patients with sepsis and septic shock.

Background

Limited data regarding the prognostic value of CRP and PCT during the course of sepsis or septic shock is available.

Methods

Consecutive patients with sepsis and septic shock from 2019 to 2021 were included monocentrically. Blood samples were retrieved from the day of disease onset (day 1), day 2, 3, 5, 7, and 10. Firstly, the diagnostic value of CRP and PCT for the diagnosis of a septic shock, as well as for the discrimination of positive blood cultures, was tested. Secondly, the prognostic value of the CRP and PCT was tested for 30-day all-cause mortality. Statistical analyses included univariab

SUBMITTER: Schupp T 

PROVIDER: S-EPMC10196281 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature