Sex-disaggregated effectiveness data reporting in COVID-19 vaccine research: a systematic review.

ABSTRACT:

Background

Sex and gender are believed to influence vaccine response. Yet, the relationship between sex and gender and COVID-19 vaccine efficacy is poorly understood and remains under-investigated.

Methods

We conducted a systematic review to determine whether and to what extent post-approval COVID-19 vaccine effectiveness (VE) studies report sex-disaggregated VE data. We searched four publication and pre-publication databases and additional grey literature sources for relevant published/preprint studies released between 1 January 2020 and 1 October 2021 (i.e., pre-Omicron era). We included observational studies providing VE estimates for one or more licensed/approved COVID-19 vaccines and including both males and females. Two reviewers independently assessed study eligibilit

SUBMITTER: Sulis G 

PROVIDER: S-EPMC10196298 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature