Radiation dose-event relationship after intraoperative radiotherapy as a boost in patients with breast cancer.

ABSTRACT:

Purpose

Intraoperative radiotherapy (IORT) can be used as a boost in combination with external whole breast irradiation. This study reports the clinical and dosimetric factors associated with IORT-related adverse events (AE).

Methods and materials

Between 2014 and 2021, 654 patients underwent IORT. A single fraction of 20 Gy was prescribed to the surface of the tumour cavity using the mobile 50-kV X-ray source. For skin dose measurement, at least four optically stimulated luminescent dosimeter (OSLD) chips were annealed and attached to the skin edge in the superior, inferior, medial, and lateral locations during IORT. Logistic regression analyses were conducted to identify factors associated with IORT-related AE.

Results

With a median follow-up period of 42 months, 7

SUBMITTER: Cho Y 

PROVIDER: S-EPMC10196364 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature