SARS-CoV-2 antigen detection by saliva; an alternative to nasopharyngeal specimen: A cross-sectional study.

ABSTRACT:

Background and aims

Saliva samples are less invasive and more convenient for patients than naso- and/or oropharynx swabs (NOS). However, there is no US Food and Drug Administration-approved severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapid antigen test kit, which can be useful in a prolonged pandemic to reduce transmission by allowing suspected individuals to self-sampling. We evaluated the performances of High sensitive AQ⁺ Rapid SARS-CoV-2 Antigen Test (AQ⁺ kit) using nasopharyngeal swabs (NPs) and saliva specimens from the same patients in laboratory conditions.

Methods

The real-time reverse transcription-polymerase chain reaction (rRT-PCR) test result was used for screening the inrolled individuals and compared as the gold standard.

SUBMITTER: Jubair M 

PROVIDER: S-EPMC10196438 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature