Chemical synthesis and mechanism of a natural product from endolichenic fungus with a broad-spectrum anti microorganism activity.

ABSTRACT:

Background

The antibiotic resistance in various bacteria is consistently increasing and is posing a serious threat to human health, prompting the need for the discovery of novel structurally featured natural products with promising biological activities in drug research and development. Endolichenic microbes have been proven to be a fertile source to produce various chemical components, and therefore these microbes have been on a prime focus for exploring natural products. In this study, to explore potential biological resources and antibacterial natural products, the secondary metabolites of an endolichenic fungus have been investigated.

Methods

The antimicrobial products were isolated from the endolichenic fungus using various chromatographic methods, and the antibacterial

SUBMITTER: Zhou X 

PROVIDER: S-EPMC10196465 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature