Dietary phytoestrogens and total and cause-specific mortality: results from 2 prospective cohort studies.

ABSTRACT:

Background

Evidence regarding dietary phytoestrogens in relation to mortality remains limited.

Objectives

The objective of the study is to examine the associations of intake of isoflavones, lignans, and coumarins with total and cause-specific mortality in US males and females.

Methods

We followed 75,981 females in the Nurses' Health Study (1984-2018) and 44,001 males in the Health Professionals Follow-up Study (1986-2018), who were free of cardiovascular disease (CVD), diabetes, or cancer at baseline. Their diet was repeatedly assessed using validated food frequency questionnaires every 2-4 y. Associations with mortality were assessed using time-dependent Cox models with adjustments for demographics, dietary and lifestyle factors, and medical history.

Results

D

SUBMITTER: Chen Z 

PROVIDER: S-EPMC10196593 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature