Creatine for Parkinson's disease.

ABSTRACT:

Background

Parkinson's disease is one of the most common neurodegenerative disorders and mitochondrial dysfunction plays an important role in its pathogenesis. Creatine is effective in improving mitochondrial function. It may therefore be useful for slowing the progression of Parkinson's disease.

Objectives

To assess the efficacy and safety of creatine used alone or as an adjuvant treatment for Parkinson's disease.

Search methods

We searched the Cochrane Movement Disorders Group Trials Register, CENTRAL (The Cochrane Library 2013, November Issue 4), MEDLINE (January 1966 to 10 November 2013), EMBASE (1974 to 10 November 2013) and two Chinese databases. We searched ongoing trials registers and conference proceedings, checked reference lists and contacted authors of inc

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC10196714 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature