Fracture risk after deprescription of bisphosphonates: Application of real-world data in primary care.

ABSTRACT:

Purpose

To compare the effect of discontinuing bisphosphonate treatment on fracture risk in postmenopausal women at high versus low risk of fracture.

Design

Retrospective, longitudinal and population-based cohort study.

Setting

Barcelona City Primary Care. Catalan Health Institute.

Participants

All women attended by primary care teams who in January 2014 had received bisphosphonate treatment for at least five years were included and followed for another five years.

Intervention

Patients were classified according to their risk of new fractures, defined as those who had a history of osteoporotic fracture and/or who received treatment with an aromatase inhibitor, and the continuity or deprescription of the bisphosphonate treatment was analyzed over fiver ye

SUBMITTER: Troncoso-Marino A 

PROVIDER: S-EPMC10196911 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature