Accelerated forgetting in healthy older samples: Implications for methodology, future ageing studies, and early identification of risk of dementia.

ABSTRACT: Accelerated long-term forgetting (ALF) has been reported in healthy older individuals, and is a possible early marker for risk of developing Alzheimer's disease (AD). The Verbal Associative Learning and Memory Test (VALMT) addresses methodological weaknesses in existing clinical tests and has detected ALF in epilepsy within an hour. We used VALMT to investigate learning and forgetting in healthy Older participants. Older (60-69 years) and Younger (19-31 years) participants were compared. Using VALMT, unrelated word pairs were learnt to criterion, then cued-recall tested at delays of 5, 30, and 55 min. Unique pairs were tested at each delay. Subjective memory complaints data was gathered, and the Wechsler Memory Scale Logical Memory test (WMS-LM; a standard clinical measure) was administere

SUBMITTER: McGibbon T 

PROVIDER: S-EPMC10196925 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature