Sigma metrics of Alinity ci system - a study on thirty-nine clinical chemistry and immunoassay parameters.

ABSTRACT:

Objectives

Sigma metrics in an invaluable and inexpensive tool used in laboratories to monitor analytical quality of the assays. Alinity ci platform is a relatively recent analytical system launched by Abbott Diagnostics, and as such performance studies on it are few. We have calculated sigma metrics of 39 clinical chemistry and immunoassay analytes on two Alinity ci systems.

Methods

Sigma metrics were calculated using results of method validation studies. Coefficient of variation (CV) was calculated according to CLSI EP 15 guidelines. Bias was calculated using three different methods i.e., proficiency testing material, alternate method comparison with existent analyzers and linearity experiment. Total allowable error limits were kept similar to or less than the ones used in

SUBMITTER: Kanani FZ 

PROVIDER: S-EPMC10197361 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature