Optimizing the COVID-19 cold chain vaccine distribution network with medical waste management: A robust optimization approach.

ABSTRACT: This paper investigates the distribution problem of the COVID-19 vaccine at the provincial level in Turkey and the management of medical waste, considering the cold chain requirements and the perishable nature of vaccines. In this context, a novel multi-period multi-objective mixed-integer linear programming model is initially presented over a 12-month planning horizon for solving the deterministic distribution problem. The model includes newly structured constraints due to the feature of COVID-19 vaccines, which must be administered in two doses at specified intervals. Then, the presented model is tested for the province of Izmir with deterministic data, and the results show that the demand can be satisfied and community immunity can be achieved in the specified planning horizon. Moreover

SUBMITTER: Ensar Isık E 

PROVIDER: S-EPMC10197550 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature