Novel candidate genes for lignin structure identified through genome-wide association study of naturally varying Populus trichocarpa.

ABSTRACT: Populus is a promising lignocellulosic feedstock for biofuels and bioproducts. However, the cell wall biopolymer lignin is a major barrier in conversion of biomass to biofuels. To investigate the variability and underlying genetic basis of the complex structure of lignin, a population of 409 three-year-old, naturally varying Populus trichocarpa genotypes were characterized by heteronuclear single quantum coherence (HSQC) nuclear magnetic resonance (NMR). A subsequent genome-wide association study (GWAS) was conducted using approximately 8.3 million single nucleotide polymorphisms (SNPs), which identified 756 genes that were significantly associated (-log₁₀(p-value)>6) with at least one lignin phenotype. Several promising candidate genes were identified, many

SUBMITTER: Bryant N 

PROVIDER: S-EPMC10197963 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature