Remnant cholesterol, stronger than triglycerides, is associated with incident non-alcoholic fatty liver disease.

ABSTRACT:

Introduction

Non-alcoholic fatty liver disease (NAFLD) is characterized by excess accumulation of triglycerides within the liver. However, whether the circulating levels of triglycerides and cholesterol transported in triglyceride-rich lipoproteins (remnant cholesterol, remnant-C) are related to the occurrence of NAFLD has not yet been studied. This study aims to assess the association of triglycerides and remnant-C with NAFLD in a Chinese cohort of middle aged and elderly individuals.

Methods

All subjects in the current study are from the 13,876 individuals who recruited in the Shandong cohort of the REACTION study. We included 6,634 participants who had more than one visit during the study period with an average follow-up time of 43.34 months. The association between lipid

SUBMITTER: Cheng Y 

PROVIDER: S-EPMC10198261 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature