Calorie-restricted diet mitigates weight gain and metabolic abnormalities in obese women with schizophrenia: a randomized controlled trial.

ABSTRACT:

Background

Obesity is a prevalent health problem in patients with schizophrenia, and calorie restriction diet (CRD) achieved effective weight loss and metabolic improvement; however, these have not been rigorously evaluated in obese patients with schizophrenia.

Objective

To measure the effects of CRD on weight loss and metabolic status in hospitalized obese women with schizophrenia during a 4-week period.

Methods

Participants were randomly assigned to two groups in a 1:1 ratio. The intervention group (n = 47) was asked to follow a CRD and the control group (n = 48) a normal diet for 4 weeks. Outcomes of body weight, body composition, as well as metabolic parameters were measured at baseline and following the intervention period.

Results

Forty-five

SUBMITTER: Zhang L 

PROVIDER: S-EPMC10198382 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature