Biomarkers of hypoxic-ischemic encephalopathy: a systematic review.

ABSTRACT:

Background

Current diagnostic criteria for hypoxic-ischemic encephalopathy in the early hours lack objective measurement tools. Therefore, this systematic review aims to identify putative molecules that can be used in diagnosis in daily clinical practice (PROSPERO ID: CRD42021272610).

Data sources

Searches were performed in PubMed, Web of Science, and Science Direct databases until November 2020. English original papers analyzing samples from newborns > 36 weeks that met at least two American College of Obstetricians and Gynecologists diagnostic criteria and/or imaging evidence of cerebral damage were included. Bias was assessed by the Newcastle-Ottawa Scale. The search and data extraction were verified by two authors separately.

Results

From 373 papers, 30 met the in

SUBMITTER: Caramelo I 

PROVIDER: S-EPMC10199106 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature