Association between ACTN3 R577X genotype and risk of non-contact injury in trained athletes: A systematic review.

ABSTRACT:

Purpose

The aim of this study was to review, systematically, evidence concerning the link between the ACTN3 R577X polymorphism and the rates and severity of non-contact injuries and exercise-induced muscle damage in athletes and individuals enrolled in exercise training programs.

Methods

A computerized literature search was performed in the electronic databases PubMed, Web of Science, and SPORTDiscus, from inception until November 2020. All included studies compared the epidemiological characteristics of non-contact injury between the different genotypes of the ACTN3 R577X polymorphism.

Results

Our search identified 492 records. After the screening of titles, abstracts, and full texts, 13 studies examining the association between the ACTN3 genotypes and the rate and s

SUBMITTER: Zouhal H 

PROVIDER: S-EPMC10199131 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature