Cross-sectional associations between cortical thickness and physical activity in older adults with spontaneous memory complaints: The MAPT Study.

ABSTRACT:

Background

Age-related changes in brain structure may constitute the starting point for cerebral function alteration. Physical activity (PA) demonstrated favorable associations with total brain volume, but its relationship with cortical thickness (CT) remains unclear. We investigated the cross-sectional associations between PA level and CT in community-dwelling people aged 70 years and older.

Methods

A total of 403 older adults aged 74.8 ± 4.0 years (mean ± SD) who underwent a baseline magnetic resonance imaging examination and who had data on PA and confounders were included. PA was assessed with a questionnaire. Participants were categorized according to PA levels. Multiple linear regressions were used to compare the brain CT (mm) of the inactive group (no PA at all) with

SUBMITTER: Raffin J 

PROVIDER: S-EPMC10199140 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature