Heart rate response and recovery during exercise predict future delirium risk-A prospective cohort study in middle- to older-aged adults.

ABSTRACT:

Background

Delirium is a neurocognitive disorder characterized by an abrupt decline in attention, awareness, and cognition after surgical/illness-induced stressors on the brain. There is now an increasing focus on how cardiovascular health interacts with neurocognitive disorders given their overlapping risk factors and links to subsequent dementia and mortality. One common indicator for cardiovascular health is the heart rate response/recovery (HRR) to exercise, but how this relates to future delirium is unknown.

Methods

Electrocardiogram data were examined in 38,740 middle- to older-aged UK Biobank participants (mean age = 58.1 years, range: 40-72 years; 47.3% males) who completed a standardized submaximal exercise stress test (15-s baseline, 6-min exercise, and 1-min recov

SUBMITTER: Gao L 

PROVIDER: S-EPMC10199142 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature