Association between base excess and 28-day mortality in sepsis patients: A secondary analysis based on the MIMIC- IV database.

ABSTRACT:

Objective

The relationship between base excess (BE) and 28-day death in sepsis patients remains to be elucidated. The aim of our clinical study is to explore the association of BE with 28-day mortality in patients with sepsis by using a large sample, multicenter Medical Information Mart for Intensive Care IV (MIMIC-IV) database.

Methods

We extracted the data of 35,010 patients with sepsis from the MIMIC-IV database, in which we used BE as an exposure variable and the 28-day mortality as an outcome variable, respectively, so as to explore the impact of BE on the 28-day mortality of patients with sepsis after adjusting for covariates.

Results

BE and the 28-day mortality of patients with sepsis appeared to have a U-shaped relationship. The calculated inflection points we

SUBMITTER: Yuan J 

PROVIDER: S-EPMC10199177 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature