Diffuse alveolar hemorrhage in children with interstitial lung disease: Determine etiologies!

ABSTRACT:

Objective

Diffuse alveolar hemorrhage (DAH) in children is a rare condition resulting from different underlying diseases. This study aimed at describing characteristics and diagnostic measures in children with ILD (children's interstitial lung disease, chILD) and DAH to improve the diagnostic approach by increasing clinician's awareness of diagnostic shortcomings.

Patients and methods

A retrospective data analysis of patients with ILD and DAH treated in our own or collaborating centers between 01/07/1997 and 31/12/2020 was performed. Data on clinical courses and diagnostic measures were systematically retrieved as case-vignettes and investigated. To assess suitability of diagnostic software-algorithms, the Human Phenotype Ontology (HPO) was revised and expanded to optimize c

SUBMITTER: Knoflach K 

PROVIDER: S-EPMC10199423 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature