Metagenomics reveals the habitat specificity of biosynthetic potential of secondary metabolites in global food fermentations.

ABSTRACT:

Background

Fermented foods are considered to be beneficial for human health. Secondary metabolites determined by biosynthetic gene clusters (BGCs) are precious bioactive compounds with various biological activities. However, the diversity and distribution of the biosynthetic potential of secondary metabolites in global food fermentations remain largely unknown. In this study, we performed a large-scale and comprehensive investigation for the BGCs in global food fermentations by metagenomics analysis.

Results

We recovered 653 bacterial metagenome-assembled genomes (MAGs) from 367 metagenomic sequencing datasets covering 15 general food fermentation types worldwide. In total, 2334 secondary metabolite BGCs, including 1003 novel BGCs, were identified in these MAGs. Bacillaceae,

SUBMITTER: Du R 

PROVIDER: S-EPMC10199516 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature