Comparison of High-Flow Nasal Cannula with Conventional Oxygen Therapy in Patients with Hypercapnic Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.

ABSTRACT:

Purpose

This study aimed to evaluate the clinical outcomes of high-flow nasal cannula (HFNC) compared with conventional oxygen therapy (COT) in patients with hypercapnic chronic obstructive pulmonary disease (COPD), including arterial partial pressure of carbon dioxide (PaCO₂), arterial partial pressure of oxygen (PaO₂), respiratory rate (RR), treatment failure, exacerbation rates, adverse events and comfort evaluation.

Patients and methods

PubMed, EMBASE and the Cochrane Library were retrieved from inception to September 30, 2022. Eligible trials were randomized controlled trials and crossover studies comparing HFNC and COT in hypercapnic COPD patients. Continuous variables were reported as mean and standard derivation and calculated by weighted mean d

SUBMITTER: Zhang L 

PROVIDER: S-EPMC10199684 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature