Real-World Experience of Methotrexate in the Treatment of Skin Diseases: an Italian Delphi Consensus.

ABSTRACT:

Background

After decades of use, methotrexate displays an established safety and efficacy profile in both in-hospital and outpatient settings. Despite its widespread use, there is surprisingly little clinical evidence to guide daily practice with methotrexate in dermatology.

Objectives

To provide guidance for clinicians in daily practice for areas in which there is limited guidance.

Methods

A Delphi consensus exercise on 23 statements was carried out on the use of methotrexate in dermatological routine settings.

Results

Consensus was reached on statements that cover six main areas: (1) pre-screening exams and monitoring of therapy; (2) dosing and administration in patients naïve to methotrexate; (3) optimal strategy for patients in remission; (4) use of folic a

SUBMITTER: Damiani G 

PROVIDER: S-EPMC10200012 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature