Association of Caffeine Consumption and Brain Amyloid Positivity in Cognitively Normal Older Adults.

ABSTRACT:

Background

Several epidemiological studies have reported the protective role of caffeine on health outcomes; however, it remained debatable on caffeine consumption and brain amyloid positivity.

Objective

We aimed to determine the relationship between caffeine consumption and brain amyloid pathology in cognitively normal older adults.

Methods

The dataset used for analysis in this cross-sectional study was selected from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) Study. Multivariable logistic regression analyses were performed to explore the association between caffeine consumption and amyloid positivity using odds ratios (ORs) and 95% confidence intervals (CIs).

Results

In total, 4,394 participants were included in the final analysis. No signific

SUBMITTER: Zheng YB 

PROVIDER: S-EPMC10200149 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature