Implicit Motor Sequence Learning in People with Mild to Moderate Parkinson's Disease: Behavior and Related Brain Function.

ABSTRACT:

Background

Deficits in motor learning could be an important explanation for the balance and gait impairments characteristic of people with Parkinson's disease (PD). Empirical studies often report that so-called implicit motor sequence learning is impaired in people with PD, but the results are inconclusive. Altered brain activity during implicit motor sequence learning has also been reported for people with PD in comparison to healthy individuals.

Objective

To investigate implicit motor sequence learning and associated neural correlates in individuals with mild to moderate PD.

Methods

Fifty-seven participants with PD and 34 healthy participants, all ≥60 years of age, performed the serial reaction time task (SRTT) during the acquisition of functional magnetic resonance

SUBMITTER: Freidle M 

PROVIDER: S-EPMC10200162 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature