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Temporal Dementia and Cognitive Impairment Trends in the Very Old in the 21st Century.


ABSTRACT:

Background

Long-increasing dementia incidence and prevalence trends may be shifting. Whether such shifts have reached the very old is unknown.

Objective

To investigate temporal trends in the incidence of dementia and cognitive impairment and prevalence of dementia, cognitive impairment, Alzheimer's disease, vascular dementia, and unclassified dementia among 85-, 90-, and ≥ 95-year-olds in Sweden during 2000-2017.

Methods

This study was conducted with Umeå 85 + /Gerontological Regional Database data from 2182 85-, 90-, and ≥ 95-year-olds in Sweden collected in 2000-2017. Using logistic regression, trends in the cumulative 5-year incidences of dementia and cognitive impairment; prevalences of dementia, cognitive impairment, Alzheimer's disease, and vascular dementia; and Mini-Mental State Examination thresholds for dementia diagnosis were estimated.

Results

Dementia and cognitive impairment incidences decreased in younger groups, which generally showed more-positive temporal trends. The prevalences of overall dementia, cognitive impairment, and Alzheimer's disease were stable or increasing; longer disease durations and increasing dementia subtype classification success may mask positive changes in incidences. Vascular dementia increased while unclassified dementia generally decreased.

Conclusion

The cognitive health of the very old may be changing in the 21st century, possibly indicating a trend break.

SUBMITTER: Weidung B 

PROVIDER: S-EPMC10200221 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Temporal Dementia and Cognitive Impairment Trends in the Very Old in the 21st Century.

Weidung Bodil B   Lövheim Hugo H   Littbrand Håkan H   Wahlin Johanna J   Olofsson Birgitta B   Gustafson Yngve Y  

Journal of Alzheimer's disease : JAD 20230101 1


<h4>Background</h4>Long-increasing dementia incidence and prevalence trends may be shifting. Whether such shifts have reached the very old is unknown.<h4>Objective</h4>To investigate temporal trends in the incidence of dementia and cognitive impairment and prevalence of dementia, cognitive impairment, Alzheimer's disease, vascular dementia, and unclassified dementia among 85-, 90-, and ≥ 95-year-olds in Sweden during 2000-2017.<h4>Methods</h4>This study was conducted with Umeå 85 + /Gerontologic  ...[more]

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