Low serum 25-hydroxyvitamin D levels are associated with liver injury markers in the US adult population.

ABSTRACT:

Objective

To examine the associations between serum 25-hydroxyvitamin D (25(OH)D) levels and serum liver enzymes in a representative sample of US adults.

Design

The cross-sectional study sample consisted of 24 229 adults with data on serum 25(OH)D levels and serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and gamma-glutamyl transaminase (GGT) concentrations, in addition to data on other potential confounders. Multivariate logistic regression and linear regression were applied to assess the associations between serum 25(OH)D levels and ALT, AST, ALP and GGT concentrations.

Setting

The National Health and Nutrition Examination Survey, 2001-2006.

Participants

The cross-sectional study sample consisted of 24 229 ad

SUBMITTER: He X 

PROVIDER: S-EPMC10200490 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature