Relationship between gestational acrylamide exposure and offspring's growth: a systematic review and meta-analysis of cohort studies.

ABSTRACT:

Objective

To estimate the current evidence regarding the association between gestational acrylamide (AA) exposure and offspring's growth.

Design

Systematic review and meta-analysis.

Setting

A systematic literature search for relevant publications was conducted using PubMed, Medline, Embase, Web of Science databases from inception to 26 April 2019. The standardised mean difference (SMD) or OR with 95 % CI was selected as the effect sizes and was calculated using a random effects model.

Results

Five cohort studies including 54 728 participants were identified. Offspring's birth weight was significantly lower in high AA exposure group than in low AA exposure group (SMD -0·05, 95 % CI -0·09, -0·02, P = 0·005). There was also an association between maternal AA expos

SUBMITTER: Zhan Y 

PROVIDER: S-EPMC10200512 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature