Effect of targeted intervention on C-terminal agrin fragment and its association with the components of sarcopenia: a scoping review.

ABSTRACT:

Background

C-terminal Agrin Fragment (CAF) has emerged as a potent biomarker for identifying sarcopenia. However, the effect of interventions on CAF concentration and the association of CAF with sarcopenia components are unclear.

Objective

To review the association between CAF concentration and muscle mass, muscle strength, and physical performance among individuals with primary and secondary sarcopenia and to synthesize the effect of interventions on the change in the level of CAF concentration.

Methods

A systematic literature search was conducted in six electronic databases, and studies were included if they met the selection criteria decided a priori. The data extraction sheet was prepared, validated, and extracted relevant data.

Results

A total of 5,158 rec

SUBMITTER: Kumar P 

PROVIDER: S-EPMC10200783 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature