Early childhood household instability, adolescent structural neural network architecture, and young adulthood depression: A 21-year longitudinal study.

ABSTRACT: Unstable and unpredictable environments are linked to risk for psychopathology, but the underlying neural mechanisms that explain how instability relate to subsequent mental health concerns remain unclear. In particular, few studies have focused on the association between instability and white matter structures despite white matter playing a crucial role for neural development. In a longitudinal sample recruited from a population-based study (N = 237), household instability (residential moves, changes in household composition, caregiver transitions in the first 5 years) was examined in association with adolescent structural network organization (network integration, segregation, and robustness of white matter connectomes; M_age = 15.87) and young adulthood anxiety and depression

SUBMITTER: Hardi FA 

PROVIDER: S-EPMC10200816 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature