Molecular modeling study of natural products as potential bioactive compounds against SARS-CoV-2.

ABSTRACT:

Context

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 infection and responsible for millions of victims worldwide, remains a significant threat to public health. Even after the development of vaccines, research interest in the emergence of new variants is still prominent. Currently, the focus is on the search for effective and safe drugs, given the limitations and side effects observed for the synthetic drugs administered so far. In this sense, bioactive natural products that are widely used in the pharmaceutical industry due to their effectiveness and low toxicity have emerged as potential options in the search for safe drugs against COVID-19. Following this line, we screened 10 bioactive compounds derived from cholesterol fo

SUBMITTER: Ribeiro R 

PROVIDER: S-EPMC10201022 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature