Cohort profile: four early uranium processing facilities in the US and Canada.

ABSTRACT:

Purpose

Pooling of individual-level data for workers involved in uranium refining and processing (excluding enrichment) may provide valuable insights into risks from occupational uranium and external ionizing radiation exposures.

Methods

Data were pooled for workers from four uranium processing facilities (Fernald, Mallinckrodt and Middlesex from the U.S.; and Port Hope, Canada). Employment began as early as the 1930s and follow-up was as late as 2017. Workers were exposed to high concentrations of uranium, radium, and their decay products, as well as gamma radiation and ambient radon decay products. Exposure and outcome data were harmonized using similar definitions and dose reconstruction methods. Standardized mortality ratios (SMR) were estimated.

Results

In total,

SUBMITTER: Golden AP 

PROVIDER: S-EPMC10201456 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature