The effectiveness of the anti-tumor necrosis factor therapy infliximab in neuro-Behcet's disease: a systematic review and meta-analysis.

ABSTRACT:

Objective

To study the effectiveness of infliximab for the treatment of refractory central neuro-Behçet's disease.

Methods

In this systematic review and meta-analysis, the research question was designed using the 'Population, Intervention, Comparator, and Outcomes' (PICO) model and the search methodology was developed according to the PRISMA statement. The study was registered on PROSPERO. Web of Science, PubMed, and Cochrane Library databases were searched for articles published in English between January 2000 and January 2020. Data were analysed using Meta-Essentials software, version 10.12. Treatment effect size was determined by a random effects model. Interstudy heterogeneity was explored using I² statistics. Cumulative meta-analysis was conducted to assess t

SUBMITTER: Mohammed RHA 

PROVIDER: S-EPMC10201531 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature