The mediating effect of leisure activities in the relationship between depression and cognitive decline in middle age and older adults in Taiwan.

ABSTRACT:

Background

Depression can affect the development of cognitive functions, and there are many people with depressive symptoms and cognitive decline in the aging population. The role of mediators between depressive symptoms and the subsequent cognitive decline remains unclear. We aimed to investigate whether depressive symptoms can slow down cognitive decline through a mediator.

Methods

A total of 3,135 samples were collected in 2003, 2007, and 2011. This study used the CES-D10 and SPMSQ (Short Portable Mental State Questionnaire) to measure depression and cognitive functions. The effect of depression trajectory on the subsequent cognitive dysfunction was analyzed using multivariable logistic regression, and the mediating effect was analyzed using the Sobel test.

Results

SUBMITTER: Hung YC 

PROVIDER: S-EPMC10201706 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature