Effect of driving pressure on early postoperative lung gas distribution in supratentorial craniotomy: a randomized controlled trial.

ABSTRACT:

Background

Neurosurgical patients represent a high-risk population for postoperative pulmonary complications (PPCs). A lower intraoperative driving pressure (DP) is related to a reduction in postoperative pulmonary complications. We hypothesized that driving pressure-guided ventilation during supratentorial craniotomy might lead to a more homogeneous gas distribution in the lung postoperatively.

Methods

This was a randomized trial conducted between June 2020 and July 2021 at Beijing Tiantan Hospital. Fifty-three patients undergoing supratentorial craniotomy were randomly divided into the titration group or control group at a ratio of 1 to 1. The control group received 5 cmH₂O PEEP, and the titration group received individualized PEEP targeting the lowest DP. The p

SUBMITTER: Liu F 

PROVIDER: S-EPMC10201743 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature