VX-765 has a Protective Effect on Mice with Ovarian Injury Caused by Chemotherapy.

ABSTRACT:

Background

Malignant tumors continue to remain a main global public health issue. In the past 40 years, due to strides made in multi-disciplinary comprehensive treatment schemes for patients suffering from malignant tumors, especially chemotherapy schemes, the survival rate has been greatly improved in such patients. This group can be expected to maintain their fertility or have restored endocrine function following successful malignant tumor treatment. Therefore, focusing on the ovarian damage caused by chemotherapy in women of childbearing age is vital in order to protect their fertility and improve their quality of life.

Objective

This study attempted to evaluate whether VX-765 possesses an ovarian protective effect in ovarian injury induced by chemotherapy in the mice mo

SUBMITTER: Lee P 

PROVIDER: S-EPMC10202083 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature